QMB Biointeractions Programme

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The meeting programme is currently under development and more detail will be available in the near future.

The meeting will focus on the field of biomolecular interactions including, protein-protein, protein-small molecule and protein-DNA interactions.

The meeting will start at 8.30am Sunday 28 August and conclude in the early afternoon of Monday 29 August

Sunday 28th August
Biointeractions and Health Chaired by Ren Dobson (University of Melbourne and Universtiy of Canterbury) and Grant Pearce (University of Canterbury)
8.50-9.00 am	Introduction Emily Parker, University of Canterbury
9.00-9.40 am	Michael Hecht (B1) Princeton University Alzheimer's Disease:Protein-Protein Interactions that Cause Disease and Protein-Small Molecule Interactions that May Lead to a Cure
9.40-10.00 am	Celine Valéry (B2) University of Canterbury Functional peptide assemblies: structural features and biomimetic applications
10.00-10.30 am	Morning Tea
10.30-11.00 am	Andrew Hill (B3) University of Melbourne Intercellular trafficking of proteins and RNA in neurodegenerative diseases
11.00-11.30 am	Ashley Buckle (B4) Monash University Conformational plasticity in alpha-1 antitrypsin: the role of dynamics in serpin misfolding, aggregation and disease
11.30-12.00 pm	Mike Griffin (B5) University of Melbourne Methionine oxidation induces amyloid fibril formation by apolipoprotein A-I
12.00-1.00 pm	Lunch
Bionteractions in Nature Chaired by Vic Arcus (University of Waikato) and Juliet Gerrard (University of Canterbury)
1.00-1.40 pm	Tom Laue (B6) University of New Hampshire Proximity energy framework for biochemistry
1.40-2.00 pm	Craig Hutton (B7) University of Melbourne Solid phase synthesis of covalently cross-linked peptides: application to the study of dityrosine-linked A-beta dimers
2.00-2.30 pm	Wayne Patrick (B8) Massey University The weird stuff in proteomes, and its role in the evolution of new biomolecular functions
2.30-3.00 pm	Bostjan Kobe (B9) University of Queensland Using structural information to predict peptide-protein interactions: application to protein kinases, MHC class II and nuclear localisation
3.00-3.30 pm	Afternoon Tea
3.30- 3.50 pm	Xiaolin Sun (B10) The New Zealand Institute for Plant and Food Research GRAS proteins: A functionally required unfoldome from the plant kingdom
3.50- 4.10 pm	Davide Mercadante (B11) University of Auckland Interaction dynamics of PME-pectin complexes reveals enzyme specificity and a novel strategy of progressive catalysis
4.10- 4.30 pm	Sebastian Reichau (B12) University of Canterbury Tackling tuberculosis: Development of new potent inhibitors for an antibacterial drug target
4.30- 4.50 pm	Muhammad Boota Faisal (B13) Massey University Unraveling the protein architecture of the plant-specific Onset of Leaf Death1 (OLD1) protein by X-ray crystallography

5.30 pm - 7.00 pm	Mixer and Poster Session (Trades Area)

Monday 29th August
Biomolecular Interactions & Structure Chaired by Conan Fee (University of Canterbury) and Wayne Patrick (Massey University)
8.45-9.30 am	David Millar (B14) The Scripps Research Institute Nucleic acid -- protein interactions at the single-molecule level
9.30-10.00 am	Nick Dixon (B15) University of Wollongong The E coli chromosomal replicase: design principles for a dynamic molecular machine
10.00-10.30 am	Morning Tea
10.30-11.00 am	Sheena McGown (B16) Monash University Structural basis for the inhibition of the essential Plasmodium falciparum aminopeptidases
11.00-11.30 am	Chris Squire (B17) University of Auckland Hijacking Ubiquitination: orf, structure prediction, and the SCF ubiquitin ligase complex
11.30-12.00	James Murphy (B18) Walter and Eliza Hall Institute of Medical Research Molecular characterization of the haematopoietic pseudokinase-domain containing proteins, Jak2 and Mlkl
12.00-1.00 pm	Lunch
1.00-1.30 pm	Julian Eaton-Rye (B19) University of Otago Auxiliary proteins of photosystem II: tuning the enzyme for optimal activity
1.30-2.00 pm	Vic Arcus (B20) University of Waikato The VapBC toxin-antitoxin protein complex is a tunable metabolic regulator
2.00-2.30 pm	Kurt Krause (B21) University of Otago Orf virus chemokine binding protein maintains tight binding across chemokine families
2.30-3.00 pm	Grant Pearce (B22) University of Canterbury How does Rubisco interact with Rubisco Activase?

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