QMB Epigenetics Programme

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The meeting will have sessions focussing on: Epigenetics in lower eukaryotes, Epigenetics in disease, Epigenetics in Plants, Histone structure and roles in epigenetics, the role of methylation in epigenetics.

Thursday 1st September
Functional organization of the nucleus and its inheritance Chair: Professor Tony Reeve
9.10-9.15am	Welcome
9.15-10.00am	Professor Rob Martienssen (Q1): Replication-coupled silencing and spreading with RNAi
10.00-10.30 am	Morning Tea, Trades Area
Chromatin Modifiers Chair: Prof. David Tremethick
10.30-11.15am	Dr Clare Stirzaker (Q2): Long range epigenetic deregulation in Cancer
11.15-11.45am	Lucia Daxinger (Q3): A saturation screen for epigenetic modifiers in the mouse
11.45-12.00	Dr Helen Fitzsimons (Q4): The histone deacetylase Rpd3 regulates long-term courtship memory in Drosophila
12.00-1.00pm	Lunch, Trades Area
Developmental epigenetics - joint session
1.00-1.45pm	TBA (Q5)
1.45-2.15pm	TBA (Q6)
2.15-2.30pm	TBA (Q7)
2.30-2.45pm	Suyin Chong (Q8): The effects of maternal ethanol consumption on offspring epigenotype and phenotype in the mouse
2.45-3.00pm	Alice Johnstone (Q9): The role of epigenetics in Human obesity
3.00-3.30pm	Afternoon Tea, Trades Area
Joint Bioinformatics, Development, Epigenetics session: From sequences to betting
3.30-4.15pm	Prof Arthur Lander (Q10)
4.15-5.00pm	Prof Julio Licinio (Q11)
5.00-5.45pm	Prof Andy Feinberg (Q12): The epigenetic basis of common Human disease

6.30-8.00pm	Posters, Trades area

Friday 2nd September
Histone variants in early development Chair: Dr Justin O'Sullivan
8.45-9.30am	Prof David Tremethick (Q13): The role of histone variants in remodelling chromatin during early development and differentiation
9.35-10.00am	Dr Tracy Hale (Q14): The role of histone H1 and HP1 in tumorigenesis
10.00-10.30 am	Morning Tea, Trades Area
Epigenetic Control during Development Chair: Dr Tracy Hale
10.30-11.15am	Dr Jean Finnegan (Q15): Flicking the switch on Polycomb regulated genes
11.15-11.45am	Dr Lee Wong (Q16): Embryonic stem cells and ALT cancer cells share key chromatin players in the maintenance of telomeric chromatin integrity
11.45-12.00	Dr Erin Macaulay (Q17): The intersect of placental epigenetics with placental function and dysfunction
12.00-1.00pm	Lunch, Trades Area
Determing phenotype Chair: Dr Austen Ganley
1.00-1.45pm	Dr Owen Marshall (Q18): Neocentromere formation in well-differentiated liposarcoma tumours
1.45-2.00pm	Kuljeet Singh (Q19): Bovine αS1-casein gene expression during involution and re-initiation of lactation is associated with acute DNA methylation changes at a STAT5-binding site in the αS1-casein promoter
2.00-2.15pm	Euan Rodger (Q20): Mapping the methylome of Myelodysplasia
2.15-2.30pm	Zoe Vincent (Q21): Epigenetic regulation of matrix metalloproteinases and their inhibitors in parturition
2.30-2.45pm	Jenny Rhodes (Q22): Regulation of pluripotency genes by cohesin
2.45-3.00pm	Hester Roberts (Q23): Allele specific methylation and parent of origin effects - discovering novel imprinted genes
3.00-3.30pm	Afternoon Tea, Trades Area
Global chromatin Chair: Prof. Rob Martienssen
3.30-4.00pm	Dr Julia Horsfield (Q24): Understanding human cohesinopathy syndromes using zebrafish
4.00-4.15pm	Mr Ralph Grand (Q25): Mitochondrial-nuclear DNA interactions affect nuclear transcript levels.
4.15-4.30pm	Anirudda Chatterjee (Q26): Genome-scale DNA methylation mapping: unraveling inter-individual variation
4.30-4.45pm	Ying Liu (Q27): Epigenetic regulation of gene expression at high altitude environment
4.45-5.00pm	Dr Andrew Cridge (Q27): Gene identity and positions act as determinants of spatial organization

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