Kidney Programme

MOLECULAR MECHANISMS IN RENAL DISEASE
31st August - 2 September, 2008
Rydges Hotel, Queenstown, New Zealand

31st August, Sunday evening	Inigo's Bar, Rydges, - social mixer Presentation by Dick Bunton, Rockburn Wines, Central Otago
1 September, Monday	Welcome: Rob Walker, University of Otago
	Plenary lecture: Jeff Sands (K1), Emory University, Georgia, USA Regulation of renal urea transport by vasopressin
	Emerging concepts in nephrogenesis and nephron maintenance Mike Eccles (K2), University of Otago, New Zealand Molecular genetics of PAX2 and PAX8 in kidney cell development and turnover Alan Davidson (K3), Harvard Medical School, USA Nephron formation in Zebrafish John Bertram (K4), Monash University, Australia Nephron number: developmental determinants and links to race, birthweight and Hypertension Cherie Stayner (K5), University of Otago, New Zealand Testing rapamycin as a treatment for polycystic kidney disease
	Renal concentrating mechanism and defects - transporters Chair: Fiona McDonald, University of Otago David Weiner (K6), University of Florida, USA Ammonia transport in the 21st century - new insights into new mechanisms Rob Walker (K7), University of Otago, New Zealand Lithium, aquaporins, and renal water handling Stefan Broer (K8), School of Biochemistry and Molecular Biology, Australian National University, Australia Physiology and Pathophysiology of renal neutral amino acid transport Daniel Markovich (K9), University of Queensland, Australia Calcium oxalate nephrolithiasis: lessons from transporter null mice John Leader (K10), University of Otago, New Zealand The effect of long term lithium administration on renal function in the rat
2 September, Tuesday	Kidney fibrosis and development Chair: Dan Markovich, University of Queensland Tony Poole (K11), University of Otago, New Zealand Primary cilia mechanosensation in kidney fibrosis Demming Gong (2), School of Biological Sciences, The Maurice Wilkins Centre for Molecular BioDiscovery, University of Auckland, New Zealand A copper (II)-selective chelator ameliorates diabetes-evoked renal fibrosis and albuminuria, and suppresses pathogenic transforming growth factor ß activation in the kidneys of rats used as a model of diabetes Rita Lee (K13), AgResearch Ltd., Ruakura Research Centre, New Zealand Abnormalities in kidney development in cattle cloned by somatic cell nuclear transfer (SCNT) Zoltan Endre (K14), University of Otago, New Zealand Early detection of acute kidney injury Posters
2 September, Tuesday	Renal injury and Fibrosis Chair: David Harris, University of Sydney David Harris (K15), University of Sydney, Australia Novel therapies for interstitial inflammation Glenda Gobe (K16), University of Queensland, Australia Is chronic disease of the ageing kidney a case of renal regeneration gone wrong? Phil Poronnik (K17), University of Queensland, Australia Insights into renal albumin handling Richard Kitching (K18), Monash University, Australia Mechanisms of leukocyte activation and recruitment in glomerulonephritis Aven Lee (K19), University of Queensland, Australia Aspartyl aminopeptidase and ClC-5 - further insights into regulation of renal albumin uptake Closing remarks: Zoltan Endre

POSTERS

	TITLE	AUTHORS	INSTITUTIONS
K20	PROSTATE CANCER CELL-LINE SPECIFIC SIGNATURES OF ANDROGEN RECEPTOR AND CAVEOLIN-1: IS THERE A LINK TO DEVELOPMENT OF ANDROGEN INDEPENDENCE?	N.C. Bennett, J.D. Hooper, D.W. Johnson, G.C. Gobe	University of Queensland, Queensland University of Technology, PAH, Brisbane, AUSTRALIA
K21	EFFECT OF A HIGH FAT DIET ON THE DISTRIBUTION OF ANGIOTENSIN II AT1- AND AT2-RECEPTORS IN SPRAGUE-DAWLEY RATS	Edward Thynne, Gerard Davis	University of Otago, NEW ZEALAND
K22	ACUTE PRENATAL ALCOHOL EXPOSURE RESULTS IN A LOWER NEPHRON NUMBER, HYPERTENSION AND AN INCREASED GLOMERULAR FILTRATION RATE	Stephen P. Gray, Kate Denton, John F. Bertram, Karen M. Mortiz	Monash University, Victoria, University of Queensland, AUSTRALIA.
K23	A MATHEMATICAL TGF MODEL	J. Graybill1, Alex James, Mike Plank, Tim David, Zoltán Endre	University of Canterbury, University of Otago, NEW ZEALAND
K24	FIBROBLAST PRIMARY CILIA IN A SHEEP MODEL OF ARPKD	Mike Jennings, Kim Parker, Mike Eccles, Tony Poole	University of Otago, Dunedin, NEW ZEALAND
K25	A WHOLE ORGAN MATHEMATICAL MODEL OF DYNAMIC AUTOREGULATION IN THE RAT KIDNEY	N. Kleinstreuer, T. David, M. J. Plank, Z. Endre	University of Canterbury,3 University of Otago, Christchurch, NEW ZEALAND
K26	INTERACTION OF COMMD FAMILY PROTEINS WITH THE EPITHELIAL SODIUM CHANNEL	Yongfeng Liu, Fiona McDonald	University of Otago, Dunedin, NEW ZEALAND
K27	CHANGES IN RENAL EXPRESSION OF GENES INVOLVED IN INOSITOL METABOLISM DURING DIABETES	Hao-Han George Chang, Kerry M. Loomes	University of Auckland, NEW ZEALAND
K28	MECHANISM BY WHICH COMMD1 DOWN-REGULATES HUMAN EPITHELIAL SODIUM CHANNEL ACTIVITY	Ying Ke, F. McDonald	University of Otago, Dunedin, NEW ZEALAND
K29	dENaC UBIQUITINATION AND REGULATION BY COMMD1	McDonald, FJ., Chang, T., Ke, Y., Ly, K.	University of Otago, Dunedin, NEW ZEALAND
K30	AGE-INDUCED EZRIN CLEAVAGE: GENERATION OF A DOMINANT-NEGATIVE FORM OF EZRIN?	McRobert EA, Bach L	Monash University, Alfred Hospital, Prahran, Victoria, AUSTRALIA
K31	KRUPPEL-LIKE FACTOR 4 DOES NOT REDUCE TGF-ß1 INDUCED TUBULAR CELL INFLAMMATORY RESPONSES	E. Mreich, S. Saad, X.M. Chen, W. Qi, C.A. Pollock	University of Sydney, Royal North Shore Hospital, NSW, AUSTRALIA; University of Melbourne, St Vincent's Hospital, Victoria, AUSTRALIA
K32	RAPAMYCIN TREATMENT OF Pkd1-/- EMBRYOS AMELIORATES THE EFFECTS OF RENAL CYSTIC DISEASE	Justin Shields, Michael Eccles, Cherie Stayner	University of Otago,Dunedin, NEW ZEALAND
K33	BIOCHEMICAL CHARACTERIZATION OF SOLUBLE HLA-DR: A POTENTIAL URINARY BIOMARKER FOR RENAL TRANSPLANT REJECTION	Yi-Tian Ting, Amy C. Dunn, Richard Parker, Ralph W. Jack, Linda Berney-Meyer, Robert Walker, Alexander D. McLellan	University of Otago, Dunedin, NEW ZEALAND
K34	SODIUM AND HYPERTENSION: IS BLOOD VESSEL FUNCTION AFFECTED BY DIETARY SODIUM INTAKE?	Todd, A.S., MacGinley, R.J., Schollum, J.B.W., Sutherland, W.H.F., Mann, J.I., Walker, R.J.	University of Otago, Dunedin, NEW ZEALAND
K35	AUGMENTED NEPHRON NUMBER AND METANEPHRIC DEVELOPMENT IN BETAGLYCAN HETEROZYGOUS MICE	Kenneth A. Walker, Sunder Sims-Lucas, Mai Sarraj, Georgina Caruana, Kaye L. Stenvers, John F Bertram	Monash University, Prince Henry's Institute of Medical Research, Clayton, Victoria, AUSTRALIA, Nationwide Children's Hospital, Columbus, Ohio, USA
K36	MODULATION OF RENAL VASCULAR FUNCTION FOLLOWING ADMINISTRATION OF CARBON MONOXIDE DURING HYPOTHERMIC PULSATILE PERFUSION IN A MODEL OF TRANSPLANT ISCHAEMIA REPERFUSION INJURY	I. Winburn, Y. Yao, J. Hill, R. Walker, Z. Endre, I. Sammut	University of Otago, Dunedin and Christchurch, NEW ZEALAND